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NetSeed is a software package for identifying the seed sets of networks (as defined in Borenstein et al., 2008) and is available as an online tool and as a Perl module.



» NetSeed>Web

  Determine the seed set of a network online.

» NetSeed>Perl

  Download the Perl module to add NetSeed's functionality to your custom analysis programs.

» NetSeed Manual

  Learn how to use NetSeed in your analysis.

Trying it out? Check out our example networks.



Borenstein et al. (2008) introduced the seed set in the context of metabolic networks

The seed set of a network is the minimal subset of nodes in a directed network required to access every node in the network. For a metabolic network constructed with nodes representing compounds and edges representing reactions that link substrates to products, the seed set therefore represents the minimal subset of the compounds in the network that cannot be synthesized from other compounds in the network (and hence are exogenously acquired) and whose existence permits the production of all other compounds in the network. The seed set of a metabolic network was shown to serve as a successful proxy for the habitat of the organism. For a complete description of the science and algorithms behind network seed analysis, please refer to Borenstein et al. (2008).



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