CoMiDA
CoMiDA
CoMiDA is an algorithm for designing simple communities with some predefined metabolic capacities.
Using
CoMiDA
» CoMiDA>Code (GitHub)
Download the CoMiDA source code from GitHub repository.
Learn how to obtain, compile, and use CoMiDA in your analysis.
Understanding
CoMiDA
CoMiDA is a novel algorithm for identifying minimal sets of microbial species that collectively provide the enzymatic capacity required to synthesize a set of desired target product metabolites from a predefined set of available substrates. The CoMiDA algorithm integrates a graph theoretic representation of network flow with the set cover problem in an integer linear programming (ILP) framework to simultaneously identify possible metabolic paths from substrates to products while minimizing the number of species required to catalyze these metabolic reactions.
Citing
CoMiDA
Alexander Eng and Elhanan Borenstein, An algorithm for designing minimal microbial communities with desired metabolic capacities. Bioinformatics, 32(13), 2016.